Biliary Tract Cancers (BTCs)

What are Biliary Tract Cancers (BTCs)?

Biliary tract cancers (BTCs) are a group of rare and aggressive gastrointestinal (GI) cancers that occur in the bile ducts and gallbladder. These cancers may affect the liver and could be caused by inflammation or blockage of the bile ducts over time.

The bile ducts are a series of thin tubes that go from the liver to the small intestine. Their main job is to allow bile, a fluid made in the liver, to go from the liver directly into the small intestine, or into the gallbladder for storage. Bile helps the body digest fat in food.

Early-stage BTCs affecting the bile ducts and gallbladder typically do not cause symptoms. Most new cases of BTCs are diagnosed at an advanced stage, which means the cancer may have already spread to other parts of the body.

What are biliary tract cancers?

Bile duct cancer

  • Starts in the bile ducts
  • Is usually diagnosed in people 65 years of age or older

Gallbladder cancer

  • Forms in the tissues of the gallbladder
  • Is usually diagnosed in people 65 years of age or older
  • May be found when the gallbladder is checked for gallstones or removed

What are the symptoms of bile duct cancer and gallbladder cancer?

The most common symptoms include:

  • Yellowing of the skin and eyes

  • Dark urine

  • Gray-colored stool

  • Abdominal pain

  • Weight loss

  • Fever

Online Support

You don’t have to face cancer alone. Explore our list of AstraZeneca and independent resources to find a community you can connect with.

YOUR Cancer

A community engagement and recognition program that catalyzes diverse organizations and individuals across public health and oncology to bring about meaningful change.

GI Cancers Alliance

The GI Cancers Alliance works to raise awareness and provide education and advocacy for people living with GI cancers like gallbladder cancer.

Cholangio­carci­no­ma Foundation (CCF)

CCF is dedicated to improving the quality of life for people living with cholangio­carci­no­ma. CCF has become a leader in research, education, and community support. From finding the right healthcare team with the specialist map, to finding a mentor, CCF may be a valuable resource for patients and caregivers.